Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e5ea5dcc3f5fd9ed3749c2e254484b8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B29-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C30B7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
filingDate |
2011-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391a9e8c14302dd516d03b5fcae1d635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_085b3f4319f459c562d035842b794176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bbc70377739037ed4cfc9053153f8d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94ba119cf3bcd9d594f05b2d6fb1f740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e1695266ab80edafa81d96a7504ee15 |
publicationDate |
2017-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
PE-20170923-A1 |
titleOfInvention |
A CRYSTALLINE FORM OF (R) -7-CHLORO-N- (QUINUCLIDIN-3-IL) BENZO [B] THIOPHENE-2-CARBOXAMIDE MONOHYDRATED HYDROCHLORIDE |
abstract |
Refers to the crystalline forms I and II of the hydrochloride compound of (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxaxmide monohydrate, where the crystalline form I is characterized by its X-ray powder diffraction pattern having peaks expressed as 2 (theta) 4.50; 9.04; 14.60; 15.14; 15.80; 16.60; 18.16; 18.44; 19.48; 21.74 and 25.46 ± 0.20 degrees; and crystalline form II is characterized by its X-ray powder diffraction pattern having peaks expressed as 2 (theta): 4.48; 9.00; 13.58; 15.62; 16.48; 19.02; 19.44; 22.46 and 25.00 ± 0.20 degrees. It also refers to a pharmaceutical composition and a production process. This compound is an agonist of the alpha-7 nicotinic receptor and is useful in the treatment of CNS disorders associated with cognitive deficiencies. |
priorityDate |
2010-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |