abstract |
The present invention relates to alkylamide substituted pyridyl derivatives of formula (I) that act as modulators of responses of heterodimeric cytosines Interleukin 12 and 23 (IL-12 and IL-23) and / or Interferon alfa. Where: R1 is C1-3 alkyl substituted by 0-7 deuterium atoms; R2 is methyl, ethyl, etc .; R3 has the formula (ii); R3aa is C1-6 alkyl, etc .; R3ab, R3ac or R3ad are hydrogen, pyrazolyl, etc .; R4 and R5 are hydrogen |