| abstract |
The present invention relates to antimicrobial compositions and more specifically carboxylic acid derivative compositions. these compositions have improved solubility, stability, and tolerability. These compositions are useful for intravenous administration to treat, prevent, or reduce the risk of infection. Said quinalone carboxylic acid derivative is a D-glucitol, 1-deoxy-1- (methylamino) -, 1- (6-amino-3,5-difluoro-2-pyridinyl) -8-chloro-6-fluoro- 1,4-dihydro-7- (3-hydroxy-1-azetidinyl) -4-oxo-3-quinolinecarboxylate (salt), OR said quinolone carboxylic acid derivative is crystalline D-glucitol, 1-deoxy-1- ( methylamino) -, 1- (6-amino-3,5-difluoro-2-pyridinyl) -8-chloro-6-fluoro-1,4-dihydro-7 - (3-hydroxy-1-azetidinyl) -4- oxo-3-quinolinecarboxylate trihydrate (salt) |