| abstract |
Referring to AKR1C3 inhibitors of formula (I) and processes for their preparation, use of them for the treatment and / or prophylaxis of diseases and use of them for the production of drugs for the treatment and / or prophylaxis of diseases, in special for bleeding disorders and endometriosis, where: X is carbon, etc; And it is carbon, etc; R3 is hydrogen or halogen; R4 is hydrogen, C1-C6 alkyl, etc; R5 is hydrogen, C1-C6 alkyl, etc. Preferred compounds: 17- (pyridin-3-yl) ester-1,3,5 (10), 16-tetraen-3-carboxamide; 17- (5-methoxypyridin-3-yl) ester-1,3,5 (10), 16-tetraen-3-carboxamide |