| abstract |
A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof functions as an antagonist of mGluR2, and is applicable as a therapeutic agent for neurological disorders related to glutamate dysfunction and diseases involving mGluR2, such as Alzheimer's disease: where R is a hydrogen atom, a C1-C6 alkyl group or the like, R1 is a C1-C6 alkyl group, a C1-C6 alkoxy group or the like, R2 is a halogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group or the like, R3 is a hydrogen atom, a C1-C6 alkyl group or the like, and R4 is a C1-C6 alkyl group or the like |