| abstract |
REFERRING TO A HETEROCICLIC COMPOUND OF FORMULA (I), WHERE R5 IS -CH2CH3 OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF. A FAVORITE COMPOUND IS N- {1S- [2R- (6,6'-DIFLUORO-3 '- {4S-HYDROXY-1- [2S- (2S-METHYLAMINE-PROPIONYLAMINE) -BUTYRYL] -PYRROLIDIN-2R-ILMETHYL} -1H, 1'H- [2,2 '] BIINDOLYL-3-ILMETYL) -4S-HYDROXY-PYRROLIDIN-1-CARBONYL] -PROPYL} -2S-METHYLAMINE-PROPIONAMIDE. SUCH COMPOUNDS ARE USEFUL IN THE TREATMENT OF A PROLIFERATIVE DISORDER |