| abstract |
REFERRING TO A COMPOUND OF FORMULA I, WHERE R53 IS PHENYL, SUBSTITUTED OR NOT WITH 1-3 HALOGEN SUBSTITUTES, -CN, -OH, C1-C6 ALKYL, C1-C6 HALOALKYL, -NH2, OR SUBSTITUTED BIPHENYL, FELTREUSED IN PHENYL OTHERS; R54 C1-C4 ALKYL, C1-C4 HALOALKYL, -CH2OH, OR 2 R54 TAKEN TOGETHER WITH THE CARBON ATOMS WITH WHICH IT IS UNITED, FORM A CARBOCYCLIC RING OF 3-6 MEMBERS COMPLETELY OR PARTIALLY SATURATED, AMONG OTHERS; p ES 0-3; q IS 0-2; n IS 1-3; A IS HETEROARYL CE 5-10 MEMBERS CONTAINING 1 OR MORE NITROGEN ATOMS WHICH MAY OR MAY NOT BE SUBSTITUTED FOR 1-3 HALOGEN SUBSTITUENTS, OH, CN, C1-C4 ALKYL, AMONG OTHERS. PREFERRED COMPOUNDS ARE: 1-BENZOTHIAZOL-6-IL-3- (4-METHYL-PYRIDIN-3-IL) -IMIDAZOLIDIN-2-ONA; 1- (2-CHLORO-PYRIDIN-4-IL) -3- (4-METHYL-PYRIDIN-3-IL) -IMIDAZOLIDIN-2-ONA; AMONG OTHERS. SUCH OSN INHIBITING COMPOUNDS OF 17 ALPHA-HYDROXYLASE / LIASA-C17-20 USEFUL IN THE TREATMENT OF CANCER |