| abstract |
IT REFERS TO A PHARMACEUTICAL COMPOSITION WHICH IS AN EMULSION OF OIL IN WATER CONTAINING: A) AN INTERNAL HYDROPHOBIC PHASE IN A QUANTITY OF 5 TO 30% BY WEIGHT THAT CONTAINS BENZYL ALCOHOL AND 2-OCTILDODECANOL; B) AN EXTERNAL HYDROPHILE PHASE IN AN AMOUNT OF 70 TO 95% BY WEIGHT CONTAINING WATER, LOWER ALKANOLS, POLYHYDRIC ALCOHOLS, POLYETHYLENE GLYCOLS AND PROPYLENE GLYCOLS; C) A POLYMERIC SURFACTANT SUCH AS ACRYLATES, CROSPOLYMERS OF ALKYL ACRYLATE (C10-C30) OR CELLULOSE ESTERS IN AN AMOUNT OF 1 TO 2% BY WEIGHT OF THE COMPOSITION; D) A BIO / MUCOADHESIVE SUCH AS A CARBOMER IN AN AMOUNT OF 0.5 TO 1.5% BY WEIGHT OF THE COMPOSITION; AND E) AN ACTIVE PRINCIPLE NOT SOLUBLE IN WATER SUCH AS CICLOPIROX, NIFURATEL, IMIQUIMOD, ACICLOVIR, METRONIDAZOL, AMONG OTHERS, WHICH IS IN A QUANTITY OF 0.5 TO 15% BY WEIGHT. SUCH COMPOSITION IS PRESENTED IN THE FORM OF A LOTION, CREAM OR GEL USEFUL IN THE TREATMENT OF VAGINAL INFECTIONS AND INFLAMMATION |