| abstract |
REFERS TO A POLYMORPHIC FORM OF THE COMPOUND 3-CHLORO-6- (HYDROXIMETHYL) -2-METHYL-5- [4 - ({4- (TRIFLUOROMETHYL) OXY] PHENYL} OXY) PHENYL] -4 (1H) -PYRIDINONE, CHARACTERIZED BY AN XRD DIFRACTOGRAM IN 2 THETA ANGLE TERMS WITH A MARGIN OF ERROR OF APPROXIMATELY + -0.1 DEGREES AT 5.0, 10.1, 14.2, 15.1, 16.4, 18.9, 19 , 6, 20.0, 25.4, 26.0, 26.5 AND 28.0 CORRESPONDING RESPECTIVELY TO INTERPLANE DISTANCES d TO 17.6, 8.8, 6.2, 5.4, 5.8, 4.7, 4.5, 4.4, 3.5, 3.4, 3.4 and 3.2A. IT ALSO REFERS TO A PREPARATION PROCEDURE AND A PHARMACEUTICAL COMPOSITION. SAID COMPOUND HAS ACTIVITY ON PLASMODIUM FALCIPARUM, BEING USEFUL FOR THE TREATMENT OF INFECTIONS SUCH AS MALARIA |