http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PE-20081703-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-00 |
| filingDate | 2008-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6139be587887be199e8a7a2b5719c420 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b759896ddfde2a6a37d764b800091038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59cc2f33bde9d86ebfdabac39fc6b5ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66c8a2986ce4f83135833b5459084446 |
| publicationDate | 2009-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PE-20081703-A1 |
| titleOfInvention | NEW TRICYCLIC DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| abstract | REFERRING TO A TRICYCLIC COMPOUND OF FORMULA (I), WHERE A IS AN AROMATIC OR NON-AROMATIC CYCLE CONTAINING 5, 6 OR 7 LINKS THAT MAY CONTAIN 1 OR 2 HETEROATOMS SUCH AS O, S AND N AND N 'ARE 0, 1 OR 2 WHERE THE SUM OF n AND n 'IS BETWEEN 0 AND 4; R3 IS ARYL OR HETEROARYL; X IS A C1-C6 ALKYLENE OPTIONALLY SUBSTITUTED WITH OXYGEN, CYCLOALKYLENE, ARYLENE, HETEROARYLENE OR SO2; R1 AND R2 ARE H OR A COMPOUND OF FORMULA (II); Y IS C = O O CH2; R5 IS H; R6 IS H OR A -NR7R7 'OR -CH2-NR7R7' GROUP; R7 AND R7 'ARE H, C1-C6 ALKYL, AMONG OTHERS. PREFERRED COMPOUNDS ARE: N - ({(4aR) -3 - [(4'-CHLORO [1,1'-BIPHENYL] -2-IL) METHYL] -2,3,4,4a, 5,6-HEXAHYDRO- 1H-PIRAZINO [1,2-a] QUINOLIN-8-IL} CARBONYL) -4 - ({(1R) -3- (DIMETHYLAMINE) -1 - [(PHENYLSULFANIL) -MEthyl] PROPYL} AMINO) -3-NITROBENZENOSULFONAMIDE , N - ({(4aR) -3 - [(4'-CHLORO [1,1'-BIPHENYL] -2-IL) METHYL] -2,3,4,4a, 5,6-HEXAHYDRO-1H-PIRAZINE [1,2-a] QUINOLIN-8-IL} CARBONYL) -4 - ({(1R) -3 - ((1R, 5S) -3-AZABICYCLO [3.1.0] HEX-3-IL) -1- [(PHENYLSULPHANIL) -MEthyl] PROPYL} AMINO) -3-NITROBENZENOSULFONAMIDE, N - ({(10aß) -2 - [(4'-CHLORO [1,1'-BIPHENYL] -2-IL) METHYL] -1, 2,3,4,10,10a-HEXAHYDROPIRAZINO [1,2-a] INDOL-8-IL} CARBONYL) -4 - ({(1R) -3- (DIMETHYLAMINO) -1 - [(FENYLSULFANIL) METHYL] PROPYL } AMINO) -3-NITROBENZENOSULFONAMIDE. IT ALSO REFERS TO A PREPARATION PROCEDURE AND A PHARMACEUTICAL COMPOSITION. SUCH COMPOUNDS HAVE PRO-APOPATHIC ACTIVITY AND ARE USEFUL IN THE TREATMENT OF CANCER |
| priorityDate | 2007-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.