| abstract |
REFERRING TO A PHENYL-DERIVED COMPOUND OF FORMULA (A), WHERE G IS NO, F, Cl, NO2, N (CF3) 2, AMONG OTHERS; Q IS H, C1-C20 ALKYL, CN, NO2, AMONG OTHERS; L IS A LINK, CO, SO2, SO, AMONG OTHERS; AND IS A LINK OR A SPACER; U IS A MANAGING AGENT; X- IS CF3S (O) 2O-, IODIDE ANION, PERCHLORATE, AMONG OTHERS; K IS N + (R1) (R2) (R3) X- O W; R1, R2 AND R3 ARE ALKYL, ARALKYL, AMONG OTHERS; W IS A FLUORINE ISOTOPE. PREFERRED COMPOUNDS ARE: 3-CYANE-4-FLUORO-N- {6- [3 - ((2R, 4S, 5R) -4-HYDROXY-5-HYDROXY-METHYL-TETRAHYDRO-THIOFEN-2-IL) -5- METHYL-2,6-DIOXO-3,6-DIHYDRO-2H-PYRIMIDIN-1-IL] -HEXYL} -BENZAMIDE, 3-CYANE-4-FLUORO-N- {4- [3 - ((2R, 4S, 5R) -4-HYDROXY-5-HYDROXIMETHYL-TETRAHYDRO-FURAN-2-IL) -5-METHYL-2,6-DIOXO-3,6-DIHYDRO-2H-PYRIMIDIN-1-ILCARBAMOIL] -BUTYL} -BENZAMIDE, 3-CYANE-4-FLUORO-N- {2- [3 - ((2R, 4S, 5R) -4-HODROXY-5-HYDROXY-METHYL-TETRAHYDRO-FURAN-2-IL) -5-METHYL-2, 6-DIOXO-3,6-DIHYDRO-2H-PYRIMIDIN-1-ILCARBAMOYL] -ETHYL} -BENZAMIDE, AMONG OTHERS. IT ALSO REFERS TO A COMPOSITION THAT INCLUDES THESE COMPOUNDS. THESE COMPOUNDS ARE USEFUL FOR RADIOMAGING WITH 18F AND ARE USEFUL IN THE DIAGNOSIS BY IMAGES |