| abstract |
REFERS TO A COMPOUND OF FORMULA Ic WHERE R1 IS F, Cl, Br, AMONG OTHERS; R2 IS 3,4,5-TRIFLUORPHENYL; 3,4-DIFLUORPHENYL, AMONG OTHERS; X IS AN ANION. THE PREFERRED COMPOUNDS ARE: (3R) -3 - [(3-FLUOROPHENYL) - (3,4,5-TRIFLUORBENZYL) -CARBAMOYLOXY] -1- (2-OXO-2-PHENYLETHYL) -1-AZONIABICICLO [2.2.2] OCTANE, BROMIDE; (3R) -3 - [(3-FLUORPHENYL) - (3,4,5-TRIFLUORBENZYL) -CARBAMOYLOXY] -1- (2-OXO-2- (4-FLUORPHENYL) ETHYL) -1-AZONIABICICLO [2.2.2 ] OCTANE-BROMIDE; AMONG OTHERS. A PHARMACEUTICAL COMPOSITION AND A PREPARATION PROCEDURE ARE ALSO REFERRED. THE DESCRIBED COMPOUNDS ARE MODULATORS OF THE MUSCARINE M3 RECEPTOR, USEFUL IN THE TREATMENT AND PREVENTION OF RESPIRATORY DISEASES SUCH AS ASTHMA, CHRONIC BRONCHITIS, EMPHYSEMA AND RELATED OTHERS |