http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PE-20080070-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| filingDate | 2007-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17de72810211a9a382c910635a428bf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16f8fdd8be5954a2b9d13c92a7ca98f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f21daebc8f1b00fc89039331c9b1cccf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f927405a5b158415e0574ac3124b333e |
| publicationDate | 2008-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PE-20080070-A1 |
| titleOfInvention | INDOLOBENZAZEPINE DERIVATIVES FUSED TO CYCLOPROPYL AS INHIBITORS OF THE POLYMERASE NS5B OF THE HEPATITIS C VIRUS |
| abstract | REFERS TO COMPOUNDS OF INDOLOBENZAZEPINE DERIVATIVES FUSED TO CYCLOPROPYL OF FORMULA (I) WHERE R1 IS CO2R5 OR CONR6R7, WHERE R5 IS H OR ALKYL (C1-C6); R6 IS H, ALKYL (C1-C6), ALKYL (C1-C6) SO2, CYCLOALKYL (C3-C7) SO2, AMONG OTHERS; R7 IS H O (C1-C6) ALKYL; R2 IS A COMPOUND OF FORMULA (i) O (ii), WHERE R8 IS H, ALKYL (C1-C6), CYCLOALKYL (C3-C7), AMINOCARBONYL, AMONG OTHERS; R3 IS H, HALO, (C1-C6) ALKYL, OH, AMONG OTHERS; R4 IS CYCLOALKYL (C3-C7). PREFERRED COMPOUNDS ARE: (+/-) - 8-CYCLOHEXIL-N- (METHYLSULFONYL) -1,1a, 2,12b-TETRAHYDRO-11-METOXY-1a- (3-METHYL-3,8-DIAZABICYCLE [3.2.1 ] OCTANE-8-CARBONYL) CYCLOPROP [d] INDOLE [2,1-a] [2] BENZAZEPINE-5-CARBOXAMIDE, (+/-) - 8-CYCLOHEXIL-N- (ETHYLSULFONYL) -1,1a, 2, 12b-TETRAHYDRO-11-METHOXY-1a- (3-METHYL-3,8-DIAZABICYCLO [3.2.1] OCTANE-8-CARBONYL) CYCLOPROP [d] INDOLO [2,1-a] [2] BENZAZEPINE-5- CARBOXAMIDE, AMONG OTHERS. IT ALSO REFERS TO A PHARMACEUTICAL COMPOSITION. SAID COMPOUNDS ARE INHIBITORS OF THE POLYMERASE NS5B OF THE HEPATITIS C VIRUS AND ARE USEFUL IN THE TREATMENT OF HEPATITIS C INFECTION |
| priorityDate | 2006-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.