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publicationDate 2007-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PE-20070806-A1
titleOfInvention PHARMACEUTICAL COMPOSITION INCLUDING A DIARYLUREA DERIVATIVE
abstract IT REFERS TO A PHARMACEUTICAL COMPOSITION INCLUDING: A) A DIARYLUREA COMPOUND SUCH AS 4 {4- [3- (4-CHLORO-3-TRIFLUOROMETILPHENYL) -UREIDO] -3-FLUOROPHENOXY} -PYRIDYL-2-CARBOXYL ACID METHYLAMIDE WHICH IS IN A QUANTITY OF 60 TO 1000MG IN THE COMPOSITION; AND B) AN ELASTASE OR KINASE INHIBITOR SUCH AS IMATINIB; AND C) A THERAPEUTIC AGENT SELECTED FROM i) A PHOSPHODIESTERASE V INHIBITOR SUCH AS SILDENAFILO, TADALAFILO, VARDENAFILO, AMONG OTHERS; ii) AN ENDOTHELIN ANTAGONIST SUCH AS BOSENTAN OR SITAXENTAN; iii) A PROSTACICLIN ANALOGUE SUCH AS TREPROSTINYL. SUCH COMPOSITION IS USEFUL FOR THE TREATMENT OF PULMONARY HYPERTENSION
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Total number of triples: 32.