| abstract |
IT REFERS TO A NUCLEIC ACID OF BINDING TO GHRELIN THAT INCLUDES: A FIRST BOX OF SECTION A CONSTITUTING APPROXIMATELY 25 CONSECUTIVE NUCLEOTIDES; A SECOND BOX OF SECTION B CONSTITUTED APPROXIMATELY OF 6 TO 8 NUCLEOTIDES; IN WHICH A 3 'TERMINAL SECTION OF NUCLEOTIDES IN THE FIRST PLACE A OF THE SECTION IS HYBRID WITH THE SECOND PLACE B OF THE SECTION, WHERE AFTER THE HYBRIDIZATION, A DOUBLE CHAIN STRUCTURE IS FORMED THAT INCLUDES A PROTUBERANCE WHICH IS MADE OF 1 TO 3 NUCLEOTIDES OF SECOND SPACE B OF THE SECTION, WITHOUT MATCHING THE BASES WITH THE FIVE CONSECUTIVE 3'-TERMINAL NUCLEOTIDES OF THE FIRST PLACE A OF THE SECTION; ALSO INCLUDES A THIRD BOX C1 CONSTITUTED BY AT LEAST ONE NUCLEOTIDE AND IS UNITED WITH ITS 3 'END TO THE 5' END OF THE SECOND BOX B OF THE SECTION; AND A FOURTH SQUARE C2 CONSTITUTED BY AT LEAST ONE NUCLEOTIDE AND IS JOINTED WITH ITS 5 'END TO THE 3' END OF THE FIRST SQUARE A OF THE SECTION FORMING A SECOND STRUCTURE IN A HELICAL FORM; IT ALSO INCLUDES A FIFTH BOX D OF THE SECTION THAT INCLUDES A SEQUENCE 5'CA (X) n3 '; AND A SIXTH BOX THAT INCLUDES AT LEAST ONE NUCLEOTIDE. A COMPOSITION THAT UNDERSTANDS YOU AND A DIAGNOSTIC AGENT. IT IS USEFUL IN THE TREATMENT OF OBESITY, EATING DISORDERS, DIABETES, TUMOR, ACROMEGALY AND REGULATION OF THE ENERGY BALANCE |