| abstract |
REFERRING TO A COMPOUND DERIVED FROM BETA-D-RIBOFURANOSILTIAZOLO [4,5-d] PYRIMIDINE OF FORMULA I, WHERE R1a, R1b AND R1c ARE H, C (O) R3, AMONG OTHERS; R2 IS H, OR5; R3 IS C1-C18 ALKYL; R5 IS H, C1-C6 ALKYL, C3-C7 ALKYL, AMONG OTHERS; WITH THE CONDITION THAT R5 IS NOT -CH3 AND WITH THE CONDITION THAT AT LEAST ONE OF R1a, R1b AND R1c IS NOT H WHEN R2 IS H. THE PREFERRED COMPOUNDS ARE: 5-AMINO-3- (5'-OL DICHLORHYDRATE -VALINYL-BETA-D-RIBOFURANOSIL) THIAZOLO [4,5-d] PYRIMIDINE-2,7-DIONA, 5-AMINO-3-BETA-D-RIBOFURANOSIL-7-METOXY-THIAZOLO [4,5-d] PYRIMIDIN -2-ONA, AMONG OTHERS. IT ALSO REFERS TO A PHARMACEUTICAL COMPOSITION. SUCH COMPOUNDS ARE USEFUL FOR THEIR IMMUNOMODULATORY ACTIVITY |