http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PE-20050773-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 |
| filingDate | 2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c588e2c724749d1a6258ba12a583b49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0e1ccdfce040388de29f527c4111266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d9843be9dfbafaf563b4f6da5405fe6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_898deb02a41fb42cc71bf207818d4daa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe2701a4c9e7860b497bd6af679dbc58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e24d93eacfd423fa60932aeb050b0f6 |
| publicationDate | 2005-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PE-20050773-A1 |
| titleOfInvention | SUBSTITUTED QUINOLINE COMPOUNDS |
| abstract | REFERS TO A QUINOLINE COMPOUND SUBSTITUTED FOR FORMULA (I) WHERE R1 IS A GROUP OF FORMULA R1a AND IS JOINED TO POSITION 2 or 3 OF THE QUINOLINE GROUP OF FORMULA I WHERE m IS AN INTEGER NUMBER FROM 0 TO 2, n IS A INTEGER NUMBER FROM 0 TO 4, p IS AN INTEGER NUMBER FROM 0 TO 5, q IS AN INTEGER NUMBER FROM 0 3, R IS A LINK OR AN INTEGER NUMBER FROM 1 TO 3; X IS -N OR -C (Ra) - WHERE Ra IS H OR R9; X1 IS -N- O -C (Rb) - WHERE Rb IS H OR R7; R2, R7, R8 AND R9 ARE SELECTED FROM HALO, -OH, -CN, ALKYL (C1-C4), ALCOXY (C1-C4) -, R5 AND R10 ARE SELECTED EACH OF H, ALKYL (C1-C4), ALKYL (C1-C4) SUBSTITUTED WITH HALO; R6 IS ALKYL (C1-C10), PYRIDYL, PHENYL OR PHENYL-ALKYL (C1-C6) -, ALKENYL (C2-C10); Y IS H, C1-C8 ALKYL, C3-C7 CYCLOALKYL-C1-C6 ALKYL, AMONG OTHERS. THE PREFERRED COMPOUNDS ARE (CARBAMOYL-PHENYL-METHYL) -AMIDE OF THE ACID (S) -2 - [(4'-TRIFLUORomethyl-BIPHENYL-2-CARBONYL) -AMINE] -QUINOLINE-6-CARBOXYL, (METILCARBAMOYL-PHENYL-METHYL) -AMIDE OF ACID (S) -2 - [(4'-TRIFLUOROMETHYL-BIPHENYL-2-CARBONYL) -AMINE] -QUINOLINE-6-CARBOXYL, [PHENYL- (2,2,2-TRIFLUORO-ETHYLCARBAMOYL) METHYL] - 2 - [(4'-TRIFLUORomethyl-BIPHENYL-2-CARBONYL) -AMINE] -QUINOLINE-6-CARBOXYL ACID AMIDE, AMONG OTHERS. QUINOLINE COMPOUNDS ARE INHIBITORS OF MICROSOMAL TRIGLYCERID TRANSFER PROTEIN (MTP) AND / OR APOLIPOPROTEIN B (APO B) SECRETION, USEFUL IN THE CONTROL OF WEIGHT AND TREATMENT OF OBESITY |
| priorityDate | 2004-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.