| abstract |
REFERS TO A PHARMACEUTICAL COMPOSITION IN THE FORM OF HYDROGEL THAT CONTAINS: a) A DIESTER OF CARBOXYL ACID WHICH IS A COMPOUND OF FORMULA: R1-O-CO-O-R2, WHERE R1 AND R2 ARE, ALKYL (C1-C6) , ALKENYL OR ALKINYL (C2-C6) WHICH MAY BE INTERRUPTED WITH ATOMS OF OXOGENO AND / OR SULFUR, CYCLOALKYL (C4-C6), HETEROCICLOALKYL, AMONG OTHERS; OR R1 AND R2 ARE UNITED WITH EACH OTHER THROUGH A C-C JOINT; IT MAY ALSO BE A PROPYLENE OR ETHYLENE CARBONATE; b) AN ALKYLALCOHOL (C2-C4) LIKE ETHANOL; c) AT LEAST ONE ACTIVE SUBSTANCE, PREFERENTIALLY AN ANDROGENIC STEROID SUCH AS 7a-METHYL-11b-FLUORO-19-NORTESTOSTERONE (eF-MENT), 7a-METHYL-19-NOR-TESTOSTERONE (MENT) OR THEIR CORRESPONDING ACETATES AND d) A POLYMER MATRIX INCLUDING AN ACRYL POLYMER OR CELLULOSE DERIVATIVE. IT ALSO REFERS TO A PHARMACEUTICAL COMPOSITION IN WHICH THE STEROID IS IN COMBINATION WITH AT LEAST ONE OTHER ACTIVE SUBSTANCE. THIS COMPOSITION IS ADMINISTERED IN A TRANSDERMAL FORM, CHARACTERIZED BY BEING RESISTANT TO TRANSPIRATION AND IS USEFUL FOR THE TREATMENT OF STEROID DEFICIENCY |