| abstract |
REFERS TO CICLOALKANINDOLS WITH FLUOR REPLACEMENT FOR FORMULA I WHERE n IS 0-1; m IS 1-3; R1 IS H, C1-C3 ALKYL, HALOGENATED CYCLOPROPYL; R2 IS 4-CHLOROPHENYL, 2,4,6-TRICHLOROPHENYL. THE PREFERRED COMPOUNDS ARE [4- (4-CHLOROBENZYL) -7-FLUORO-5- (METANSULPHONYL) -1,2,3,4-TETRAHYDROCYCLOPENTA [b] INDOL-3-IL] ACETIC ACID, {4- (1- (4-CHLOROPHENYL) ETHYL] -7-FLUORO-5-METANSULFONYL-1,2,3,4-TETRAHYDROCYCLOPENTA [b] INDOL-3-IL] ACETIC ACID [9- (4-CHLOROBENZYL) -6-FLUORO- 8-METANSULFONIL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-IL] ACETIC, AMONG OTHERS, ALSO REFERS TO A PHARMACEUTICAL COMPOSITION THAT INCLUDES A SECOND INGREDIENT SELECTED FROM AN ANTIHISTAMINE, ANTAGONISTS OF LEATHER. MENTIONED ARE USEFUL FOR THE TREATMENT OF ASTHMA, ALLERGIC RHINITIS |