| abstract |
REFERS TO SUBSTITUTED 1,3-DIAMINOPROPANE DERIVATIVES OF FORMULA I WHERE R1 IS C1-C12 ALKYL, C3-C8 CYCLOALKYL, ARYL, AMONG OTHERS; R2 IS C1-C12 ALKYL, C3-C8 CYCLOALKYL, ARYL, AMONG OTHERS; R1 AND R2 ARE ARYL, HETEROCYCLYL; R1 AND R2 TOGETHER FORM THE RADICAL - (CH2) m-, NOT SUBSTITUTED, MONO OR POLYSUSTITUTED WITH C1-C6 ALKYL, ARYL, BEING m 2-6; R3 IS H, C1-C12 ALKYL, C3-C8 CYCLOALKYL, ARYL, AMONG OTHERS; R4 IS H, C1-C12 ALKYL, C3-C8 CYCLOALKYL, AMONG OTHERS; R3 AND R4 FORM THE RADICAL - (CH2) n-, where n is 3-7; R5 AND R6 ARE C1-C12 ALKYL, C3-C8 CYCLALKYL, ARYL, AMONG OTHERS; A IS ARILO, HETEROARILO, AMONG OTHERS. PREFERRED COMPOUNDS ARE N, N-DIMETHYL- [PHENYL- (2-PYRROLIDIN-1-ILCICLOHEXYL) -MEthyl] -AMINE, N, N-DIMETHYL - [(2-MORPHOLIN-4-IL-CYCLOHEXYL) -PHENYL-METHYL] -AMINE, 4- [PHENYL- (2-PYRROLIDIN-1-IL-CYCLOHEXYL) -MEthyl] -PYRROLIDINE, AMONG OTHERS. IT ALSO REFERS TO A PROCEDURE FOR PREPARATION. THE MENTIONED COMPOUNDS ARE USEFUL FOR THE TREATMENT AND / OR PROPHYLAXIS OF PAIN, URINARY INCONTINENCE, PRURITO |