| abstract |
REFERS TO THE USE OF ONE OR MORE ALDOSTERONE ANTAGONISTS FOR THE PREPARATION OF A MEDICINE FOR THE TREATMENT OF DISEASES IN SUBJECTS WHO PRESENT A SUB-NORMAL LEVEL OF ENDOSTERONE ALDOSTERONE, SENSITIVITY TO SALT AND DIETARY CONSUMPTION OF ELEVATE SODIUM. IT ALSO REFERS TO THE USE OF ONE OR MORE ALDOSTERONE ANTAGONISTS IN SUBJECTS WHO PRESENT: a) A RATIO OF PLASMATIC ALDOSTERONE (ng / dl) TO PLASMATIC RENIN (ng / ml / hr) GREATER THAN 30; b) A RENIN PLASMA LEVEL LESS THAN OR EQUAL TO 1.0 ng / dl / hr, c) SYSTOLIC BLOOD PRESSURE OF 130 mm Hg OR A DIASTOLIC BLOOD PRESSURE GREATER THAN 85 mm Hg; d) THE SODIUM POTASSIUM RATIO LESS THAN 6; e) HIGH PLASMA LEVEL OF ENDOTHELINS; f) UNDER 55 YEARS OF AGE, AMONG OTHER CONDITIONS. ALDOSTERONE ANTAGONISTS ARE USEFUL FOR THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR DISEASE, KIDNEY DYSFUNCTION, HEPATIC DISEASE, CEREBROVASCULAR DISEASE, RETINOPATHY, NEUROPATHY, INSULINOPATIA, INSULINOPATIA, EDGE DYSFUNCTION |