http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PE-20010685-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 |
| filingDate | 2000-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_722d29e0d78e82032aed5ccabd57f108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_285027358c0eb9b6f23bfb9d2abcf0df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe289e5dc7253540aa1d11168a03e499 |
| publicationDate | 2001-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PE-20010685-A1 |
| titleOfInvention | COMPOSITION INCLUDING AN INTERLEUQUIN 1 RECEPTOR ANTAGONIST POLYPEPTIDE AND A DIARYLSULPHONYLUREA AS AN INHIBITOR OF IL-1 PROCESSING AND RELEASE |
| abstract | IT REFERS TO THE USE OF A COMPOSITION THAT INCLUDES: a) AN ANTAGONIST POLYPEPTIDE OF THE INTERLEUQUIN 1 RECEPTOR (IL-1ra), OF PREFERENCE OF A SEQUENCE (ID SEQ N ° 2) OF 169 AMINO ACIDS; b) A NON-STEROID AGENT THAT INHIBITS THE PROCESSING AND RELEASE OF IL-1 SUCH AS DIARYLSULFONYLUREA R1- (O =) S (= O) -NH-C (= O) -NH-R2; WHERE R1 AND R2 ARE A GROUP OF FORMULA II IN WHICH THE LINES --- REPRESENT DOUBLE OPTIONAL LINKS; n IS 0-3; A, B, D, E, and G ARE O, S, N, CR5R6; R5 AND R6 ARE H, C1-C6 ALKYL, HALOGEN, CYANE, AMINO, OH, AMONG OTHERS, BEING SELECTED COMPOUNDS 1- (1,2,3,5,6,7-HEXAHIDRO-s-INDACEN-4-IL) -3- [4- (1-HYDROXY-1-METHYL-ETHYL) -FURANO-2-SULFONIL] -UREA, 1- (2,6-DIISOPROPYL-PHENYL) -3- [4- (1-HYDROXY-1 -MEthyl-ETHYL-FURANE-2-SULFONIL] -UREA, 1- (4-CHLORO-2,6-DIISOPROPYL-PHENYL) -3- [3- (HYDROXY-1-METHYL-ETHYL) -BENZENOSULFONIL] -UREA, AMONG OTHERS, THE COMPOSITION MAY BE USEFUL FOR THE TREATMENT OF INFLAMMATORY DISORDERS SUCH AS RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, ASTHMA, NEURODEGENERATION, AMONG OTHERS |
| priorityDate | 1999-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419513958 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3776 |
Total number of triples: 28.