| abstract |
REFERS TO THE USE OF COMPOUNDS OF FORMULA I, WHERE R1, R2, R3 ARE H, C1-C6 ALKYL, C3-C5 ALKYL, C3-C5 ALKINYL, C3-C10 CYCLOALKYL, NR1R2; R1 AND R2 TOGETHER WITH N FORM PYRROLIDINYL, PIPERIDINYL, MORPHOLINYL, 4-METHYLPIPERAZINYL, IMIDAZOLYL; X IS H, C1-C6 ALKYL, HALO, OH, C1-C6 ALCOXYL, CYANE, CARBOXAMIDE, CARBOXYL, (C1-C6 ALCOXY) CARBONYL; A IS CH, CH2, CH- (HALOGEN), CHCH3, C = O, C = S, C-SCH3, C = NH, C-NH2, C-NHCH3, C-NHCOOCH3, C-NHCN, SO2, N; B IS CH2, CH, CH- (HALOGEN), C = O, N, NH, N-CH3; D IS CH, CH2, CH- (HALOGEN), C = O, O, N, NH, N-CH3; n IS 0-1; WHEN n IS 0, A IS CH2, CH- (HALOGEN), CHCH3, C = O, C = S, C = NH, SO2; THEN D IS CH2, CH- (HALOGEN), C = O, O, NH, N-CH3; WHEN n IS 0 AND A IS CH, C-SCH3, C-NH2, C-NHCH3, C-NHCOOCH3, C-NHCN, N; THEN D IS CH, N: AMONG OTHER CONDITIONS; USING FROM 0.2 TO 8 mg / PERSON / DOSE; A PREFERRED COMPOUND (5R) - (METHYLAMIMN) -5,6-DIHYDRO-4H-IMIDAZO- [4,5,1-ij] -QUINOLIN-2 (1H) ONA; ALSO REFERS TO USE WITH SMOOTH VASCULAR MUSCLE RELAXATION AGENTS SUCH AS SILDENAFIL, MILRINONE, PAPAVERINE, LINSIDOMINE, PHENTHOLAMINE, YOHIMBINE, PROSTAGLANDIN E1. THE FORMULA I COMPOUND MAY BE USEFUL FOR THE TREATMENT OF SEXUAL DISTURBANCES |