| abstract |
REFERS TO A PROPELLING AGENT-FREE ACTIVE SUBSTANCE CONCENTRATE CONTAINING a) FROM 75 mg / ml TO 500 mg / ml OF FORMOTEROL IN THE FORM OF A FREE BASE, b) A SOLVENT OR SUSPENSION OF PREFERENCE POLAR LIQUID SUCH AS WATER, AN AQUEOUS SOLUTION OF A SALT, OF PREFERENCE A SOLUTION OF SODIUM CHLORIDE, ETHANOL OR A MIXTURE; c) A TENSOACTIVE SUBSTANCE SUCH AS SORBITAN ESTERS, OF PREFERENCE SORBITAN TRIOLEATE, OLEIC ACID, LECITHIN; d) AN ACID SUCH AS HYDROCHLORIC ACID, NITRIC ACID, SULFURIC ACID, AMONG OTHERS; e) A PRESERVATIVE AGENT, e) AN ANTIOXIDANT, f) A COMPLEX FORMING COMPOUND SUCH AS EDTA; g) OTHER ACTIVE SUBSTANCES SUCH AS BETASYMPATHOMIMETICS, ANTI-CHOLINERGICS, ANTI-ALLERGICS, ANTAGONISTS OF LEUKOTRIENES, STEROIDS; THE pH OF THE CONCENTRATE IS FROM 2 TO 7. FORMOTEROL INHIBITS THE RELEASE OF LEUCOTRIENES, HISTAMINES, AMONG OTHERS; SO IT MAY BE USEFUL FOR THE TREATMENT OF OBSTRUCTIVE DISEASES OF THE RESPIRATORY TRACT |