| abstract |
THIS INVENTION CONCERNS COMPOUNDS OF GENERAL FORMULA I WHERE R IS PHENYL, PIRIDIN-2-ILO, -C (O) -O-LOWER RENT, C (O) -LOWER RENT, -C (O) -MORFOLINILO, -C (O) -NR'2, - (CH2) n-NR'2 O - (CH2) NO-LOWER RENT, YR 'CAN BE HYDROGEN OR LOWER RENT; AND TO PHARMACEUTICALLY ACCEPTABLE ADDITION SALTS OF THE SAME. THE COMPOUNDS DESCRIBED IN THIS APPLICATION HAVE A GOOD AFFINITY TO THE A2A RECEIVER AND THEREFORE THEY CAN BE USED IN THE CONTROL OR PREVENTION OF DISEASES BASED ON THE MODULATION OF THE ADENOSINE SYSTEM, SUCH AS ALZHEIMER'S DISEASE, PARK'S DISEASE OF DISEASE , NEUROPROTECTION, SCHIZOPHRENIA, ANXIETY, PAIN, RESPIRATORY DEFICITS, DEPRESSION, ADDITION TO DRUGS, SUCH AS AMPHETAMINE, COCAINE, OPIODIES, ETHANOL, NICOTINE, CANNABINOIDS, OR ASTHMA, RESPONSES, ALLERGY, AQUESIA, AERGIC, AQUESIA OF SUBSTANCES. IN ADDITION, THE COMPOUNDS OF THE PRESENT INVENTION MAY BE USEFUL AS SEDANTS, RELAXING MUSCULAR, ANTIPSYCHOTIC, ANTIEPILEPTIC, ANTIEPILEPTIC, ANTICONVULASIVE AND CARDIOPROTECTING AGENTS FOR SUCH DISORDERS AS THE CORTERIA DISEASE. |