| abstract |
THE PRESENT INVENTION IS RELATED TO FORMULA (A1) (A2) N-R1 (1) COMPOUNDS, N-OXIDE FORMS, PHARMACEUTICALLY ACCEPTABLE ADDITION SALTS, QUARTERLY AMINES AND STEREOCHEMICALLY ISOMERAL FORMS THEREOF, R1 IS C1-6 SUBSTITUTE RENT; -S (= O) -R8; -S (= O) 2-R8; C7-12 alkylcarbonyl; C1-6 RENTROXYCARBONYL C1-6 RENTAL OPTIONALLY REPLACED; BEING R8, RENT C1-6, ARILO1 OR HET1; (A1) (A2) N- IS THE COVALENTLY LINKED FORM OF THE INTERMEDIATE CORRESPONDING FORMULA (A1) (A2) NH, WHICH IS AN INHIBITORY PYRIMIDINE OF THE FORMULA HIV REPLICATION (II) ITS USE AS A MEDICINAL PRODUCT, THE PROCESSES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM. |