| abstract |
A COMPOUND OF THE FORMULA: OR A PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME, IN WHICH R IS CYCLLOALKYLL (C3-C11) OR CYCLLOALKENYLL (C3-C11) MONO-DI-O TRI-SUBSTITUTED, OR SIMILAR, TO IS ALKYL (C1- C7) OR ALKENYL (C2-C5) NOT SUBSTITUTED, OR ARYL MONO-, DI- OR TRI- SUBSTITUTED, AROMATIC OR SIMILAR HETERO CYCLES, AND IS HYDROGEN, HALO, AMINO OR MERCAPT, OR ALKYL (C1-C10) -M-MONO -DI- OR TRI- SUBSTITUTED, CYCLLOALKYL, CYCLLOALKYL (C3-C7) -M-, ALQUENIL (C2-C6) -M, ALQUIL (C1-C4) -NH- (ALQUIL (C1-C4)) - M-, DI-ALQUIL (C1-C4) -N- (ALQUIL (C1-C4))) - M, ARIL-M, HETEROCICLO AROMATIC OR NON-AROMATIC-M, ARIL-ALKYL (C1-C5) -MO HETEROCICLO AROMATIC OR NON-AROMATIC -ALKYL (C1-C5) -M-, WHERE M IS A COVALENT LINK, O, S, NH OR SIMILAR; Z1, Z2, Z3 AND Z4 ARE HYDROGEN OR SIMILAR; IT HAS AGONIST ACTIVITY OF THE ORLI RECEPTOR, AND THE USEFUL AS ANALGESIC OR SIMILAR IN MAMMALS. |