| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_364361dcadbe698011b0554cccff370b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C221-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C223-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 |
| filingDate |
2014-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e7cad3298c41818405b167fd8a27235 |
| publicationDate |
2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-720301-A |
| titleOfInvention |
Deuterated tetrabenazine compounds |
| abstract |
The present invention relates to novel methods of manufacturing d6-tetrabenazine and intermediates thereof. Tetrabenazine is a vesicular monoamine transporter 2 (VMAT2) inhibitor and is commonly prescribed for the treatment of chorea associated with Huntington’s disease. d6-Tetrabenazine is a deuterated analog of tetrabenazine which has improved pharmacokinetic properties when compared to the non-deuterated drug. |
| priorityDate |
2013-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |