| abstract |
Discloses compounds comprising or consisting of the oligonucleotide sequence (NAG)m, wherein N is C or 5-methylcytosine and at least one occurrence of N is 5- methylcytosine and wherein m is 7, 8, 9, 10, 11, 12, 13, 14, or 15 and wherein no inosine nucleotide is present. Also discloses use of compound to treat dystrophy type 1, spino-cerebellar ataxia 8 and/or Huntington’s disease-like 2 caused by expansion of CUG repeats. |