Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9e4cedb72851f01dadac14d585e8b17 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H05K999-99 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5025 |
filingDate |
2013-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_092382e9efb456c04654a4273597c3a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee1f41f0ac934cab112e74e2ea0fc9b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6003a842d5936c7416e5153d0490e541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84a042254a8efb923da6a59be9dba33a |
publicationDate |
2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
NZ-709648-A |
titleOfInvention |
Crystalline forms of 3-(imidazo[1,2-b] pyridazin-3-ylethynyl)-4-methyl-n-(4-[(4-methylpiperazin-1-yl) methyl]-3-(trifluoromethyl)phenyl)benzamide and its mono hydrochloride salt |
abstract |
Novel crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{ 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl} benzamide mono hydrochloride, pharmaceutical compositions thereof and methods of their preparation and use are disclosed herein. The instant application is directed to a novel crystalline Form A of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{ 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl} benzamide mono hydrochloride that maintains its form under particular thermal, humidity, and pressure stresses. |
priorityDate |
2012-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |