| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-65 |
| filingDate |
2013-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3a8147550aef99397fd81149bb3304e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b78c0a3fc917b2df54905fcfdda615c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4993dd8562586ba43caf7a6171a85770 |
| publicationDate |
2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-708091-A |
| titleOfInvention |
Stabilized insulin-like growth factor polypeptides |
| abstract |
This invention is in the field of Insulin-like growth factors 1 (IGF-1) modifications. It relates to modified IGF-1 polypeptides and modified IGF-1 precursor polypeptides wherein the cleavage of E-peptide is prevented. In particular, the present invention provides a polypeptide comprising a human IGF-1 protein variant having at least 90% identity to SEQ ID NO: 1, wherein the amino acid glycine at position 42 is mutated to serine. The invention also relates to the use of such polypeptides for treating muscle diseases and disorders. |
| priorityDate |
2012-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |