http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-628092-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6493e075b586cf5568b69116429349a8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
filingDate | 2013-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca6cbe124b9622300e65deb1a307768b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcff4fa2ffa37531d61ec7edf09649e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b20f8e8eca57d97b786360ec6ffa54b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07c96c8af42778d9905d1cffc8c3bcba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a1ef2190bae76a358752eb5993a90e0 |
publicationDate | 2017-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NZ-628092-A |
titleOfInvention | Transdermal delivery system |
abstract | The disclosure relates to a method of treating pain in a patient by applying a transdermal therapeutic system for the transdermal administration of buprenorphine for 7 days on the skin of a patient, said transdermal therapeutic system comprising a buprenorphine-containing self-adhesive layer structure comprising A) a buprenorphine-impermeable backing layer, and B) a buprenorphine-containing matrix layer on said buprenorphine- impermeable backing layer, the matrix layer comprising a) a polymer base, b) buprenorphine, and c) a carboxylic acid selected from the group consisting of oleic acid, linoleic acid, linolenic acid, levulinic acid and mixtures thereof, in an amount sufficient so that said buprenorphine is solubilized therein to form a mixture, and the carboxylic acid buprenorphine mixture forms dispersed deposits in the polymer base, and C) a skin contact layer on said buprenorphine-containing matrix layer comprising a polymer-based pressure-sensitive adhesive, and optionally wherein the buprenorphine-containing self-adhesive layer structure contains said buprenorphine in an amount of less than 0.8 mg/cm2 buprenorphine base or an equimolar amount of a pharmaceutically acceptable salt thereof. |
priorityDate | 2012-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.