abstract |
Disclosed herein are antiparasitic and pesticidal solid forms of moxidectin, including a long-acting polymeric implant. The resulting compounds may be used in veterinary compositions which are used in treating, controlling and preventing of endo- and ectoparasite infections in animals. The disclosure particularly relates to moxidectin polymorphic A form having a melting point of 210°C, prepared by the process of providing amorphous moxidectin, immersing the moxidectin into an oil bath at 190°C for about 2 to about 10 minutes, and cooling the moxidectin, thereby preparing the polymorphic A crystalline form of moxidectin. |