| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb596f03d029321340c965e75de6564a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
| filingDate |
2012-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6f5de053ad23cdb6af8de66dd759de7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e7d1be5cdbc9102f57b9982ab2dfefd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd7d2bdea52102dddc5fb338d57acda3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9af3dadb44b6e0955e4bf3b9c2a9ce20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a82f6cc86c31b0a09ff3a9670acd19c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bb2848a9d21e92d873be7db1562a2d9 |
| publicationDate |
2016-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-624338-A |
| titleOfInvention |
Method for preparing physiologically active polypeptide complex |
| abstract |
Disclosed is a method for preparing a conjugate of a physiologically active polypeptide covalently bound to a non-peptide polymer, comprising: (1) reacting physiologically active polypeptide with two or more N-terminals with a non-peptide polymer with reactive groups on 2-3 ends in a reaction solution with a pH of 4.5-7.0 comprising 45-55% organic solvent and sodium citrate to link physiologically active polypeptide with non-peptide polymer; and (2) isolating and purifying the conjugate of physiologically active polypeptide covalently bound to non-peptide polymer from the reaction mixture of the step (1). |
| priorityDate |
2011-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |