http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-618367-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4045 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4045 |
| filingDate | 2012-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be3c6c34d2e5351dfa3b1d4437996c5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a13be73a2a26826ce2c7c000af50b31e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f726e421b96ed20b2e27abce6f96221 |
| publicationDate | 2016-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-618367-A |
| titleOfInvention | Combination of panobinostat and ruxolitinib in the treatment of cancer such as a myeloproliferative neoplasm |
| abstract | Provided is the combination of ruxolitinib (A) ((R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-lyl)-3-cyclopentylpropanenitrile) and panobinostat (B) (N-hydroxy-3-[4-[[[2-(2 -methyl-1H-indol-3-yl)-ethyl]amino]methyl]phenyl]-2E-2-propenamide. The combination is useful in the treatment of cancer, particularly, myeloproliferative neoplasms. Examples of myeloproliferative neoplasms include chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), primary or idiopathic myelofibrosis (PMF), chronic neutrophilic leukemia, chronic eosinophilic leukemia, chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, hypereosinophilic syndrome, systemic mastocytosis, and atypical chronic myelogenous leukemia. |
| priorityDate | 2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.