http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-617701-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2009-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1eb7b3f009609c57f259714d4461aecb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_603bbf918d54505a168f8973cc55e68c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ceb0ef5c26820a0d34a4d45da90782d |
| publicationDate | 2015-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-617701-A |
| titleOfInvention | Methods for the treatment and prevention of age-related retinal dysfunction |
| abstract | The disclosure relates to the use of a synthetic retinal derivative for the preparation of a medicament for the treatment or prevention of age-related macular degeneration (AMO) or age-related retinal dysfunction in a subject, wherein said medicament is for administration to said subject intermittently month over a period of at least three months, wherein said synthetic retinal derivative is a 9-cis-retinyl ester of formula selected from formulae (III) to (XVI) as depicted in the specification, wherein A in each formula is CH2OR or CH(OH)OR and R forms said retinyl ester, and the ester substituent of said synthetic retinal derivative comprises a carboxylate radical of a C1-C10 monocarboxylic acid or a C2- C22 polycarboxylic acid, wherein the preferred synthetic retinal derivative is 9-cis-retinyl acetate, 9-cis-retinyl succinate, 9-cis-retinyl citrate, 9-cis-retinyl ketoglutarate, 9-cis-retinyl fumarate, 9-cis-retinyl malate or 9-cis-retinyl oxaloacetate, and wherein the synthetic retinal derivative is converted into a retinal capable of forming a functional opsin/retinal complex. |
| priorityDate | 2008-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.