| abstract |
Imidazo[1,2-B]pyridazines of formula (I) a process for their production and the use thereof. Examples of compounds of formula (I) are: 1-[4-(6-Methyl-3-phenylimidazo[1,2-b]pyridazin-2-yl)phenyl]-cyclobutanamine; 1-[4-(6-Ethyl-3-phenylimidazo[1,2-b]pyridazin-2-yl)phenyl]-cyclobutanamine; 1-{ 4-[3-Phenyl-6-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]phenyl} cyclobutanamine and Ethyl 2-[4-(1-aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxylate. The compounds are useful in treating benign neoplasia, malignant neoplasia and breast cancer. |