http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-614904-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bba710e7aaa56d8ab15a910fcd3dc5f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
| filingDate | 2009-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5637fc7d923173c68020ac6534c3bd6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3354a785562b6750592e2bde0c86b8fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d956fae356a3b7fd3315e3999df88213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fc78c739c1a645731a538a4c7c4d0ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9651a5280cdca7f656e8d1b88b349cae |
| publicationDate | 2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-614904-A |
| titleOfInvention | Mlk inhibitors and methods of use |
| abstract | Disclosed are compounds of formula (I) having an inhibitory effect on Mixed Lineage Kinases (MLK). Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases. Examples of compounds of formula (I) are: 2-phenyl-N-{ 4-[5-(3,4,5-trimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-benzyl} -acetamide and 3-phenyl-N-{ 4-[5-(3,4,5-trimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-benzyl} -propionamide. |
| priorityDate | 2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.