http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-613373-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82694e3f0301ec8f114448cdaa5bdd9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24c90e6a34424379c44e84bceac5c276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e1f5e018662d7de20b41a07222655d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_354abf02afa53839ff36e868061b29d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67552b7b38aea238f899d93ce62fa988 |
| publicationDate | 2015-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-613373-A |
| titleOfInvention | Imidazo[5,1-f][1,2,4]triazines for the treatment of neurological disorders |
| abstract | The present disclosure relates to Imidazo[5,1-f][1,2,4]Triazine compounds of Formula (I) and pharmaceutically acceptable salts thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as a method for the treatment of a PDE2 mediated disease or condition selected from the group consisting of central nervous system disorders, cognitive disorders, schizophrenia, dementia and other disorders in a mammal. Compounds of the disclosure include: 4-(azetidin-1-yl)-7-methyl-5-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazine, 4-(azetidin-1-yl)-7-methyl-5-{ 1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl} imidazo[5,1-f][1,2,4]triazine, 4-(azetidin-1-yl)-5-[5-(5-chloropyridin-2-yl)-1-methyl-1H-pyrazol-4-yl]-7-methylimidazo[5,1-f][1,2,4]triazine, N,7-dimethyl-5-{ 1-methyl-5-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-4-yl} imidazo[5,1-f][1,2,4]triazin-4-amine, And 4-(azetidin-1-yl)-7-methyl-5-{ 1-methyl-5-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-4-yl} imidazo[5,1-f][1,2,4]triazine. |
| priorityDate | 2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 407.