http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-610346-A

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filingDate 2011-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_451e9110318575b2fcb4865edfb5fc27
publicationDate 2015-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-610346-A
titleOfInvention Hyaluronic acid based formulations
abstract Discloses a method of making a soft tissue filler composition comprising the steps of: preparing a crosslinked hyaluronic acid (HA) gel comprising a mixture of a first, low molecular weight HA material and a second, high molecular weight HA material, the second, high molecular weight HA material having a weight average molecular weight of at least twice that of the first, low molecular weight material, the mixture comprising more than about 50% by weight of the first, low molecular weight HA material, wherein the HA materials are hyaluronic acid or one or more salts thereof; adjusting the HA concentration in the crosslinked HA gel to between about 15.0 mg/g and about 20.0 mg/g; preparing a solution comprising an uncrosslinked HA and/or a salt thereof having a weight average molecular weight of between at least about 1.0 MDa and about 4.0 MDa, the solution having a total HA and HA salt concentration of between about 10 mg/g and about 50 mg/g; and combining the gel with the solution.
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Total number of triples: 24.