| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 |
| filingDate |
2011-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f5c6876cbb9ce86b2e88320e90796e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4822a5549e028c4ca558dc6dbb05704d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_379f7d3378700b2842a349b7be4cd0a9 |
| publicationDate |
2015-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-609529-A |
| titleOfInvention |
A composition comprising s-[2-([[1-(2-ethylbutyl)-cyclohexyl]-carbonyl]amino)phenyl] 2-methylpropanethioate and croscarmellose sodium |
| abstract |
Disclosed is a tablet composition comprising: a) 48% to 55% by weight of dalcetrapib (S-[2-([[1-(2-ethylbutyl)-cyclohexyl]-carbonyl]amino)phenyl] 2-methylpropanethioate); b) 24% to 26% by weight of microcrystalline cellulose; c) 11% to 12% by weight of micronised crospovidone; d) 4% to 5% by weight of hydroxypropylmethyl cellulose; and e) 4% to 6% by weight of croscarmellose sodium. Also disclosed is a process for the preparation of a dalcetrapib composition comprising the following steps: a) mixing and granulating dalcetrapib, crospovidone micronized, microcrystalline cellulose, croscarmellose sodium and hydroxypropyl methylcellulose; b) spraying up to 0.5% by weight of hydroxypropyl methylcellulose in water or in 10% - 30% ethanol by weight/70% - 90% water by weight, onto the granulates obtained according to step a); c) drying the granulates; and d) blending microcrystalline cellulose, colloidal silicon dioxide and sodium stearylfumarate with the dry granulates obtained according to step c). |
| priorityDate |
2010-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |