| abstract |
Disclosed is a process for generating a compound of Formula (v) or a pharmaceutically acceptable salt or boronic acid anhydride thereof, wherein the variables are as defined in the specification, wherein the process comprising the steps of: (1) coupling a compound of Formula (i) with a compound of Formula (ii) to form a compound of Formula (iiia); (2) deprotecting the compound of Formula (iiia) to form a compound of Formula (iii); (3) coupling the compound of Formula (iii) with a compound, RcCO2H, to form a compound of Formula (iv); and (4) deprotecting the compound of Formula (iv) to form the compound of Formula (v), wherein the compounds of Formula (i), (ii), (iiia), (iii) and (iv) are as shown and defined in the specification. |