| abstract |
ABSTRACT - 603199 The disclosure relates to an orally disintegrating tablet (ODT) for the glycosidase inhibitor acarbose, wherein the tablet contains 1-30% precompacted acarbose having an average particle size of 100 to 800 μm and having a moisture content of between 0 and 5%, 40–90% water-soluble carrier selected from 10 the group mannitol, crospovidone, and polyvinyl acetate or a mixture thereof, and 1–50% water-insoluble carrier such as microcrystalline cellulose, wherein the desired properties are achieved by precompacting and premixing the ingredients with said water- insoluble carrier before tableting. |