http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-600358-A
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5053f82a7cd17c60822674b657cfb89e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2210-1067 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M35-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 |
filingDate | 2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_076b5da3af1918aaef6975d8f5b98c93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c48c5121ccef33d9304e8e82f4cb98df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32ad655c1c4699081708494ba10385c1 |
publicationDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NZ-600358-A |
titleOfInvention | Topical foam composition |
abstract | 600358 A topical foam pharmaceutical composition for rectal administration comprising rifaximin in the form of nano-sized particles, preferably having an effective particle size in the range 10 to 1000 nm is described. Also described is a method of making the composition and the use of the composition to as a medicament. Providing the composition in a pressurised dispenser having a meter for issuing a metered dose is also provided. The composition is suited for administration to the rectum, colon and/or terminal ileum of a patient for the treatment, prophylaxis, or maintenance of a disorder of the rectum, colon, terminal ileum or anus. The composition may further comprise an aqueous or non-aqueous vehicle which may be one or more phannaceutically acceptably alkanols; one or more pharmaceutically acceptable vegetable oils; or one or more phannaceutically acceptable organic esters and may further comprise surfactants, solubilizers, emulsifiers, antioxidant, preservatives, silicones, and/or 5-acetyl salicylic acid. Particularly the water soluble alkanols may be ethanol; propylene glycol; glycerol; polyethyleneglycol; polypropylene glycol; propylene glycol; a glyceryl ester; or a mixture thereof. The compositions may be prepared by: (1) heating a mixture of emulsifier and surfactant to form an oily phase; (2) separately heating a mixture of a preservative and water; (3) adding a water soluble alkanol to the preservative-water mixture and then mixing with oily phase of step (1); and (4) Adding rifaximin in the form of nanosized particles to the above mixture under stirring and adjusting the required pH to a desired value using a pH adjusting agent. |
priorityDate | 2009-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.