| abstract |
594157 Disclosed are benzenesulfonamide compounds of formula (I) where the substituents are as disclosed in the specification. Examples of compounds of formula (I) are: 2,4-Dichloro-N-[4-(1-p-tolyl-1H-pyrazol-4-yloxy)-phenyl]-benzenesulfonamide; 2,4-Dichloro-N-{ 3-chloro-4-[1-(4-chloro-3-trifluoromethyl-phenyl)-1H-pyrazol-4-yloxy]-phenyl} -benzenesulfonamide; 2,4-Dichloro-N-{ 3,5-dichloro-4-[1-(2,4-difluoro-phenyl)-1H-pyrazol-4-yloxy]-phenyl} -benzenesulfonamide. Also disclosed are pharmaceutical compositions comprising the compounds and the use of the compounds in the manufacture of a medicament for the treatment of respiratory disease. |