Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8cd0ba6260398412867b65676bfba0dc |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M36-14 |
filingDate |
2009-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91d7c19551c65a61d551d3062436c38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba362b44141ad0e54468b06c797348d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43f526cb86aeaff86755ee880a3e135d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e286d35a230e6c9ba06a325a45982583 |
publicationDate |
2013-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
NZ-593848-A |
titleOfInvention |
Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof |
abstract |
ABSTRACT - 593848 The disclosure relates to a radiopharmaceutical composition for positron emission tomography (PET) imaging of neurodegenerative diseases of the brain comprising: an effective amount of 18F-radiolabeled ((E)-4-(2-(6-(2-(2-(2-[18F]fluoroethoxy)-ethoxy)ethoxy)pyridin-3-yl)vinyl)-N-methylbenzenamine) (18FAV-45); about 10% (v/v) of ethyl alcohol; and about 90% v/v of 0.9% saline solution, wherein said saline solution comprises about 0.5% w/v sodium ascorbate, wherein the radiopharmaceutical composition has a pH of about 4.5 to about 8.0. Also disclosed is a process for preparing a mono Boc-protected vinylaniline compound of formula (I). |
priorityDate |
2008-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |