| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a708524c0adee3eb5b130dac053f9c3d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70521
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0609
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87982284be40f1822db267b124be79e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b21865403ea3f77b3517d3a06bb49b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_161f008e282aeae5169f94051410e75c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e302138aa12b7dcf9ed5a8dcff9081e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fff431f48dfb405b9421c445edefdb38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bd57a84262b7212b6334d6066ca3298 |
| publicationDate |
2012-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-593816-A |
| titleOfInvention |
Galactose-alpha-1, 3-galactose-containing n-glycans in glycoprotein products derived from cho cells |
| abstract |
Disclosed is a method for screening one or more Chinese Hamster Ovary (CHO) cells for the ability to produce glycoproteins comprising glycans containing -alpha-1-3-galactose epitopes, the method comprising: (a) providing a plurality of CHO cell populations wherein none of the plurality have been genetically engineered to produce terminal alpha-galactosyl residues on glycans; (b) culturing each of the plurality of CHO cell populations under conditions suitable for expression of a glycoprotein expression product; (c) measuring glycans containing terminal galactose-alpha-1-3-galactose residues produced by each of the plurality of CHO cells, and (d) selecting one or more of the plurality of CHO cell populations based on the presence of a target level of terminal galactose-alpha-1-3-galactose residues produced by the selected CHO cell population, wherein the CHO cells have not been transfected with an alpha-galactosyl transferase coding sequence. |
| priorityDate |
2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |