| abstract |
Abstract 592507 The present disclosure relates to calcium channel inhibitors containing compounds of formula (I), wherein L1, L2, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Disclosed are compounds such as the following: 2,2-bis(4-fluorophenyl)-N-{ (3aS*,4R*,6aR*)-2-[3-(trifluoromethyl)benzyl]octahydrocyclopenta[c]pyrrol-4-yl} acetamide, N2-(tert-butyloxycarbonyl)-N2-methyl-N1-{ (3aS,4R,6aR)-2-[3-(trifluoromethyl)benzyl]octahydrocyclopenta[c]pyrrol-4-yl} -L-leucinamide, tert-butyl (2S)-2-{ [((3aR,4S,6aS)-2-{ [3-(trifluoromethyl)phenyl]sulfonyl} octahydrocyclopenta[c]pyrrol-4-yl)amino]carbonyl} piperidine-1-carboxylate and (2S)-N-[(3aS,4R,6aR)-2-(4-fluorobenzyl)octahydrocyclopenta[c]pyrrol-4-yl]piperidine-2-carboxamide |