http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-588955-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f85b08f8307c2c093183b1254729485 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-65 |
filingDate | 2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3a3a6f3a56d7edf7a3c0d1c54ea4cab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4c43c6e7f194aed2f461cd85f85075d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e09e22848d58416f0254e5b2c215bb |
publicationDate | 2012-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NZ-588955-A |
titleOfInvention | Novel amino acid derivatives including a disulfide (disulphide), method for preparing same, and therapeutic use thereof |
abstract | The disclosure relates to amino acid derivative compounds of the formula (I) R1NH-CH(R2)-CH2-S- S-CH2-C(R3)(R4)-CONH-C(R5)(R6)-COOR7 (I) in which R1 is a (acyloxy)alkyl carbamate -C(O)-O-C(R8)(R9)-OC(O)-R10 group; R2 is a hydrocarbon chain, a methylene radical substituted by a heterocycle; R4 is a hydrogen atom and R3 is a phenyl or benzyl radical, a heteroaryl, a methylene group substituted by a heterocycle or R3 and R4 form together a saturated cycle; R5 and R6 are hydrogen, a hydrocarbon chain, a phenyl or benzyl radical or R5 and R6 form together a saturated cycle; R7 is hydrogen, a phenyl or benzyl radical, a group of the formula CR12(R13)C(O)OR14 or OCR12(R13)OC(O)R14 or OCR12(R13)OC(O)OR14. The disclosure also relates to the combined use of at least one cannabinoid derivative and/or morphine or one derivative thereof and/or Gaba derivatives for enhancing the analgesic and anti-depressive effect of these amino acid derivatives of formula (I). |
priorityDate | 2008-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.