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publicationDate 2012-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-587758-A
titleOfInvention Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
abstract Disclosed is the use of: (a) a therapeutically effective amount of progesterone; (b) a polysiloxane elastomer; and (c) a pharmaceutically acceptable hydrocarbon or glycerol esters of a fatty acid in the preparation of a medicament for treating a luteal phase defect in a patient, wherein said medicament is a monolithic intravaginal ring comprising said therapeutically effective amount of progesterone, said polysiloxane elastomer and said pharmaceutically acceptable hydrocarbon or glycerol esters of a fatty acid, and wherein the polysiloxane elastomer is present in a concentration of about 55% to about 90% by total weight of the ring.
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